We focus on the development of microfluidic devices to analyze biomolecular information from DNA, RNA, and cells with its merits of small sample consumption, rapid analysis time, high integration capability, and easy
portability.
Our lab uses digital manufacturing technology to accelerate the development of microchips that facilitate the advancement of genetic analysis applications.
The ultimate goal of our lab is to make fully integrated microdevices for genetic analysis with sample-in-answer-out capability which can be utilized in the areas of pathogen detection, environmental monitoring, and forensic analysis.
With the development of 3D printing technology utilizing various materials, microfluidic engineers are getting a lot of interest.
Our laboratory is conducting research on the development of microfluidic devices based on high-resolution 3D printing technology. This can be used to produce various microchip modules (e.g. microchannel,
reaction
chamber,
micromixer, gradient channel etc.) from three-dimensional digital data and to analyze various biological molecules such as cells an nucleic acids.
In our laboratory, we are conducting research on the development of an integrated microsystem that can perform gene-based biological analysis.
We intend to develop a system capable of on-site genetic analysis by implementing a series of processes of extracting, amplifying, and analyzing nucleic acids from viruses, bacteria, and human cells on a single chip, which can be used in various fields such as pathogen diagnosis, forensic analysis, environmental monitoring, and clinical diagnosis.
Microfluidic devices are notoriously difficult to use because of their very small structure. We are developing a microvalve or micropump that can automate the flow of these microfluids. A user is conducting research to develop a fluid system capable of performing various biological analyzes by freely manipulating all fluids by manipulating an intuitive interface on a computer.
The technology of extracting nucleic acids from cells is recognized as a hurdle in the development of microchip-based genetic analysis system. In our laboratory, we are developing microchip-based nucleic acid extraction technology by integrating negatively charged materials in microdevices or by fabricating microstructures in microdevices.
Despite various advantages, the development of 3D-printing-based biodevices has a major disadvantage of limited material selection. Therefore, our laboratory is developing a biocompatible printing resin that can 3D-print and has no cytotoxicity, which can be used for cell chips, organ chips, cancer diagnostic chips, and new drug development chips.
Yong Tae Kim Ph.D.
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- Laboratory: Room 307, Building D, Tech University of Korea
- Tel: +82-31-8041-0611
- e-mail: ytkim@tukorea.ac.kr
- Home page : https://sites.google.com/kpu.ac.kr/ytkimlab
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